Complement assay; Complement proteins

• Total blood complement level: 41 to 90 hemolytic units
• C1 level: 16 to 33 mg/dL
• C3 levels:
  • Males: 88 to 252 mg/dL
  • Females: 88 to 206 mg/dL
• C4 levels:
  • Males: 12 to 72 mg/dL
  • Females: 13 to 75 mg/dL

Note: mg/dL = milligrams per deciliter.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

Increased complement activity may be seen in:

• Cancer
• Certain infections
• Ulcerative colitis

Decreased complement activity may be seen in:

• Cirrhosis
• Glomerulonephritis
• Hereditary angioedema
• Hepatitis
• Kidney transplant rejection
• Lupus nephritis
• Malnutrition
• Systemic lupus erythematosis

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Complement Overview

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Complement Risks

Review Date: 02/10/2011
Reviewed By: Michael E. Makover, MD, professor and attending in Rheumatology at the New York University Medical Center, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)