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ALT





ALT

Definition:

A test that measures the amount of ALT in serum.


Alternative Names:
SGPT; Serum glutamate pyruvate transaminase; Alanine transaminase
How the test is performed:

Blood is drawn from a vein on the inside of the elbow or the back of the hand. The puncture site is cleaned with antiseptic, and an elastic band is placed around the upper arm to apply pressure and restrict blood flow through the vein. This causes veins below the band to fill with blood.



A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. During the procedure, the band is removed to restore circulation. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

For an infant or young child, the area is cleansed with antiseptic and punctured with a sharp needle or a lancet. The blood may be collected in a pipette (small glass tube), on a slide, onto a test strip, or into a small container. Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.


How to prepare for the test:

For infants and children:

The preparation you can provide for this test depends on your child's age and experience. For specific information regarding how you can prepare your child, see the following:


How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.


Why the test is performed:

This test is used to determine if a patient has liver damage. ALT is an enzyme involved in the metabolism of the amino acid alanine. ALT is in a number of tissues but is in highest concentrations in the liver. Injury to the liver results in release of the enzyme into the blood.




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