Table of Contents
- Overview
- Results
- Risks
- Prevention
- Images
Rapid plasma reagin test; Syphilis screening test
Normal Values
A negative test result is considered normal. However, the body does not always produce antibodies specifically in response to the syphilis bacteria, so the test is not always accurate. False-negatives may occur in persons with early- and late-stage syphilis. More testing may be needed before ruling out syphilis.
What abnormal results mean
A positive test result may mean that you have syphilis. If the screening test is positive, the next step is to confirm the diagnosis with a more specific test for syphilis, such as FTA-ABS. The FTA-ABS test will help distinguish between syphilis and other infections.
How well the RPR test can detect syphilis depends on the stage of the disease. The test is most sensitive -- almost 100% -- during the middle stages of syphilis. It is less sensitive during the earlier and later stages of the disease.
Some conditions may cause a false positive test, including:
- HIV
Lyme disease - Certain types of pneumonia
Malaria Systemic lupus erythematosus
Previous Section
Review Date: 07/26/2009
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of
Physician Assistant Studies, University of Washington, School of
Medicine; Susan Storck, MD, FACOG, Chief, Eastside Department of
Obstetrics and Gynecology, Group Health Cooperative of Puget Sound,
Redmond, Washington; Clinical Teaching Faculty, Department of
Obstetrics and Gynecology, University of Washington School of
Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director,
A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
