Euglobulin lysis time

A normal value will range from 90 minutes to 6 hours. Euglobulin clot lysis is normally complete within 2 to 4 hours.

In primary fibrinolysis (for example, caused by streptokinase administration, cancer of the prostate, shock), the euglobulin lysis time is shorter than normal.

In DIC, it is usually normal, but if all the plasmin has been consumed, the time may be prolonged.

• Decreased fibrinolysis (increased lysis time) may indicate:
  • Diabetes
  • Prematurity
• Increased fibrinolysis (shortened lysis time) may indicate:
  • Cirrhosis
  • Extensive vascular (blood vessel) trauma or surgery
  • Hereditary deficiency of fibrinogen
  • Leukemia
  • Obstetric complications (for example antepartum hemorrhage, hydatidiform mole, amniotic embolism)
  • Prostate cancer
  • Shock
  • Thrombocytopenia purpura

• Spontaneous abortion
• Primary thrombocythemia

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