The normal time it takes platelets to clump depends on temperature and may vary from laboratory to laboratory.

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

Decreased platelet aggregation may be due to:

• Autoimmune disorders that produce antibodies against platelets
• Bernard-Soulier syndrome
• Fibrin degradation products
• Glanzmann's thrombasthenia
• Medicines that block platelet formation
• Myeloproliferative disorders
• Storage pool disease
• Uremia (a result of kidney failure )
• Von Willebrand's disease

Review Date: 02/28/2011
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)