Normal values in women vary depending on when the test is done. Levels rise consistently during pregnancy and range from 40 milligrams to 100 milligrams in 24 hours.

Lower levels are found during certain phases of the menstrual cycle and after menopause.

In men, normal values range from 0.1 to 0.7 milligrams per 24 hours.

Higher-than-normal levels may be due to:

• Adrenocortical hyperplasia
• Arrhenoblastoma of ovary
• Choriocarcinoma of ovary
• Hyperadrenocorticism
• Ovarian cyst

Lower-than-normal levels may be due to:

• Amenorrhea
• Decreased ovarian function
• Fetal death
• Ovarian cancer
• Preeclampsia
• Threatened abortion
• Toxemia of pregnancy

Images

Female urinary tract

Male urinary tract

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Pregnanediol Overview

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Pregnanediol Risks

Review Date: 04/12/2009
Reviewed By: Linda Vorvick, MD, Family Physician, Seattle Site Coordinator, Lecturer, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)