Non-Small Cell Lung Cancer - Surgical Procedures

Highlights	Diagnostic Tests	Chemotherapy Treatments
Introduction	Complications	Investigative Agents
Causes	Staging Systems	Resources
Symptoms	Treatment Options by Stages	References
Risk Factors	Surgical Procedures
Lifestyle Changes	Radiation Treatments

Surgical Procedures

Surgery is performed in the following circumstances:

The surgical removal of an entire lobe or parts of a lung is the primary treatment for eligible patients in early stages of cancer. Recurrence is high after surgery, although the new tumor is often operable.
Some patients with stage IIIA cancer may also benefit from surgery (although a cure at this stage is virtually nonexistent).
Surgery is not out of the question in rare cases of metastasis when the cancer appears in a single operable location, such as the brain.

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Unfortunately, lung surgery may be too risky for patients with other lung diseases or serious medical conditions, and because lung cancers tend to occur in smokers over 50, such health problems are likely to be present. Long-term survival rates appear to be better in patients treated at hospitals that perform large numbers of lung cancer surgeries and when surgeries are performed by thoracic surgeons, who specialize in chest procedures.

Standard Surgical Procedures

The type of surgery depends on the amount of lung or other tissue that needs to be removed.

Wedge Resection or Segmentectomy. Wedge resection and segmentectomy remove only a small part of the lung; consequently, they preserve almost normal breathing function after the operation.

Lobectomy. Removal of one of the lobes of the lung is called lobectomy. The patient's lung function must be adequate before undergoing this procedure. The operation carries an overall mortality rate of 3% to 5%, with older patients having the highest risk.

Click the icon to see an illustrated series detailing surgery to remove diseased lobes of the lung.

Pneumonectomy. Pneumonectomy removes the entire lung. The procedure itself carries a mortality rate of 5% to 8%, with the oldest patients having the greatest risk. In such patients, recurrence almost always occurs.

Other Procedures

Surgical advances are allowing a wider range of options, including minimal surgeries for early cancers and surgical interventions that relieve cancer symptoms for late stages.

Thoracoscopy. Thoracoscopy is a less-invasive technique that employs a thin tube containing a miniature camera and surgical instruments. It requires much smaller incisions than open surgery and speeds recovery to the point that patients are up within hours. Such procedures can have significant drawbacks, though. For instance, one such operation, the thoracoscopic wedge resection, does not allow the surgeon to fully determine the extent of lymph node involvement or the presence of metastatic disease outside of the lung's lobes. When thoracoscopy is used for a lobectomy, it may offer little advantage in reducing postsurgical pain. Thoracoscopies are also difficult to perform and are still considered experimental.