Shingles and Chickenpox (Varicella-Zoster Virus) - Complications

Active Infection. After prodrome, a rash appears, usually on the trunk. However, the rash can develop in other areas as well, such as legs, arms, face, or neck. The rash is typically confined to one side of the body and follows the same track of inflamed nerves as the prodrome pain.

  • The rash usually starts as well-defined, small, red clear spots.
  • Within 12 - 24 hours, these pimples develop into small fluid-filled blisters. The blisters grow, merge, and become pus-filled, and are extremely painful.
  • Within about 7 - 10 days (as with chickenpox), the blisters form crusts and heal. In some cases it may take as long as a month before the skin clears completely.

Sometimes pain develops without a rash, a condition known as zoster sine herpete.

Herpes zoster (shingles) on the neck and cheek
This is a picture of herpes zoster (shingles) on the neck and cheek. The same virus that causes chickenpox is responsible for outbreaks of shingles. Outbreaks of shingles often follow the distribution of nerves in the skin. This distribution pattern is called a dermatome (see the "dermatomes" picture).

Postherpetic Neuralgia. Postherpetic neuralgia (PHN) is pain that persists for longer than a month after the onset of herpes zoster. Typical symptoms include:

  • Pain that is described as deep aching, burning, stabbing, or like an electric shock
  • Extreme sensitivity to touch or temperature changes
  • The pain is persistent, but may come and go.


Review Date: 05/03/2011
Reviewed By: Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Physician, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)