Acute Lymphocytic Leukemia - Complications

Secondary Cancer. Rarely secondary cancers, most often leukemia (generally acute myeloid leukemia), can later develop.

Psychologic and Mental Consequences

Studies are finding that survivors of childhood leukemia tend to have more psychological problems, including stress, depression, anger, and confusion, than their physically healthy siblings. As adults, they are also more likely to be unemployed or working part time. Risk for mood psychological problems may vary by treatment. A 2003 study showed that patients who received high-dose CNS radiation and methotrexate therapy had an increased risk of mood disturbances compared to those who did not receive radiation.

Recognizing this risk and getting psychologic support early may be important and helpful. Nevertheless, in one 2002 study, young survivors reported satisfaction with life, a sense of purpose, and an ability to cope because of their experiences with cancer. A 2004 study confirmed these results, reporting that 81% of adult survivors of childhood ALL had a positive self-concept.

Effects on Caregivers

One study found thatparentswho take care of children with ALLdeveloped more symptoms of post-traumatic stress disorder than their children.

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