Restless Legs Syndrome and Related Disorders - Highlights

Highlights	Complications	Resources
Introduction	Diagnosis	References
Causes	Treatment
Risk Factors	Medications

Highlights

New Drug Approved for Restless Legs Syndrome (RLS)

In 2005, ropinirole (Requip) became the first drug approved specifically for RLS. The FDA approved ropinirole for the treatment of moderate to severe RLS in adults. Ropinirole stimulates dopamine receptors in the brain. (Scientists believe that low levels of the brain chemical dopamine may cause RLS.) The drug is generally safe, but side effects may include nausea, dizziness, and drowsiness.

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Childhood RLS

?Growing pains? may really be RLS, according to a study published in the Annals of Neurology. More children than previously thought may have RLS. Doctors diagnosed RLS in nearly 6% of children who visited the Mayo Clinic?s sleep disorders center. The researchers suspect that a family history of RLS and iron deficiency are the main causes of childhood RLS.

Genetics

Scientists have confirmed that a location on chromosome 12, named RLS1, is definitely linked to RLS. In determining this genetic link, scientists studied the DNA of French Canadians who had a strong family history of RLS.

Lifestyle Tips for RLS

Adjust your desk to suit your legs. Some people with RLS find it easier to stand while working.
Adjust and maintain regular sleep patterns. Some RLS patients have an easier time sleeping earlier in the morning than in the evening.
Relax your muscles with exercise, hot baths, or leg massage.
Avoid drinking caffeine and alcohol, especially late in the day.
Eat iron-rich foods such as clams, oysters, liver, red meat, and enriched grains. Iron-rich vegetables and fruits include beans, prunes, almonds, and broccoli. Vitamin C foods, like citrus fruits, can help increase iron absorption.