Liver and spleen enlargement (hepatosplenomegaly) can occur as the
result of an inherited disorder in which the liver cannot process
glucocerebroside. The buildup of this substance in body tissues can
cause severe damage to the central nervous system in infants.
Review Date: 11/12/2010
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of
Pediatrics, University of Washington School of Medicine. Also
reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org)
