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Fatty Liver

What is the Definition of Fatty Liver?
Description of Fatty Liver
Causes of Fatty Liver
Symptoms of Fatty Liver
Diagnosis of Fatty Liver
Treatment for Fatty Liver
What Questions to ask Your Doctor About Fatty Liver?

What is the Definition of Fatty Liver?

Fatty liver is the accumulation of fat in liver cells. It is also called steatosis.

Description of Fatty Liver

Possible explanations of fatty liver include the transfer of fat from other parts of the body or an increase in the extraction of fat presented to the liver from the intestine. Other explanations are that the liver reduces the rate it breaks down and removes fat. Eating fatty foods does not by itself produce a fatty liver.

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Causes of Fatty Liver

Alcohol, obesity, starvation, diabetes mellitus, corticosteroids, poisons (carbon tetrachloride and yellow phosphorus), Cushing's syndrome, and hyperlipidemia are some causes of fatty liver. Microvesicular fatty liver may be caused by valproic acid toxicity and high-dose tetracycline or during pregnancy.

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Symptoms of Fatty Liver

Patients are often asymptomatic.

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Diagnosis of Fatty Liver

The patient may have an enlarged liver or minor elevation of liver enzyme tests. Several studies show that fatty liver is one of the most common causes of isolated minor elevation of liver enzymes found in routine blood screening.

Images of the liver obtained by an ultrasound test, CT (computed tomography) scan, or MRI (magnetic resonance imaging) may suggest the presence of a fatty liver. To be certain whether a patient has fatty liver requires a liver biopsy, in which a small sample of liver tissue is obtained through the skin and analyzed under the microscope.

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Treatment for Fatty Liver

The treatment of fatty liver is related to the cause. It is important to remember that simple fatty liver may not require treatment. The benefit of weight loss, dietary fat restriction, and exercise in obese patients is inconsistent.

Reducing or eliminating alcohol use can improve fatty liver due to alcohol toxicity. Controlling blood sugar may reduce the severity of fatty liver in patients with diabetes. Ursodeoxycholic acid may improve liver function test results, but its effect on improving the underlying liver abnormality is unclear.

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