Alport syndrome is an inherited disorder that damages tiny blood vessels in the kidneys.
Hereditary nephritis; Hematuria - nephropathy - deafness; Hemorrhagic familial nephritis; Hereditary deafness and nephropathy
Causes, incidence, and risk factors
Alport syndrome is an inherited form of kidney inflammation (nephritis). It is caused by a mutation in a gene for a protein in connective tissue, called collagen.
The disorder is uncommon, and most often affects males. Women can transmit the gene for the disorder to their children, even if they have no symptoms.
Risk factors include:
End-stage kidney diseasein male relatives
- Family history of Alport syndrome
Glomerulonephritis Hearing lossbefore age 30