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Ankylosing spondylitis

  • Definition

    Ankylosing spondylitis is a long-term disease that causes inflammation of the joints between the spinal bones, and the joints between the spine and pelvis. It eventually causes the affected spinal bones to join together.

    See also: Arthritis


    Alternative Names

    Rheumatoid spondylitis; Spondylitis; Spondylarthropathy; Seronegative bundle arthropathy


    Causes, incidence, and risk factors

    The cause of ankylosing spondylitis is unknown, but genes seem to play a role.

    The disease most often begins between ages 20 and 40, but may begin before age 10. It affects more males than females. Risk factors include:

    • Family history of ankylosing spondylitis
    • Male gender