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Basal ganglia dysfunction

  • Definition

    Basal ganglia dysfunction is a problem with the basal ganglia, the deep brain structures that help start and control movement.


    Alternative Names

    Extra-pyramidal syndrome


    Causes, incidence, and risk factors

    Conditions that cause injury to the brain can damage the basal ganglia. Such conditions include:

    • Drug overdose
    • Head injury
    • Infection
    • Liver disease
    • Metabolic problems
    • Multiple sclerosis
    • Side effects of certain medications
    • Stroke
    • Tumors

    Many brain disorders are associated with basal ganglia dysfunction. They include:

    • Dystonia
    • Huntington's disease
    • Multiple system atrophy
    • Parkinson's disease
    • Progressive supranuclear palsy
    • Wilson's disease

    This list may not be all-inclusive.