• Alternative Names

    Rock fever; Cyprus fever; Undulant fever; Gibraltar fever; Malta fever; Mediterranean fever


    Acute brucellosis may begin with mild flu-like symptoms or symptoms such as:

    • Fever
    • Abdominal pain
    • Back pain
    • Chills
    • Excessive sweating
    • Fatigue
    • Headache
    • Loss of appetite
    • Joint pain
    • Weakness
    • Weight loss

    Classically, high fever spikes occur every afternoon. "Undulant" fever derives its name from this up-and-down fever.

    Additional symptoms that may be associated with this disease:

    • Muscle pain
    • Swollen glands

    The illness may be chronic and persist for years.

    Signs and tests
    • Blood culture
    • Clean catch urine culture
    • CSF culture
    • Bone marrow culture
    • Serology detecting brucellosis antigen

    This disease may also alter the results of the following tests:

    • Quantitative immunoglobulins (nephelometry)
    • Serum immunoelectrophoresis
    • Febrile/cold agglutinins