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CMV - immunocompromised host

  • Alternative Names

    Cytomegalovirus - immunocompromised host


    Symptoms

    The symptoms of CMV infection are similar to those of mononucleosis. In fact, in a small percentage of people with mononucleosis, CMV is the cause. The symptoms of primary CMV infection are:

    • Fatigue
    • General discomfort, uneasiness, or ill feeling (malaise)
    • Joint stiffness
    • Loss of appetite
    • Muscle aches or joint pain
    • Night sweats
    • Prolonged fever
    • Sore throat
    • Swelling of the lymph nodes
    • Weakness
    • Weight loss

    In immunocompromised people, CMV can attack specific organs. The major symptoms of these organ-specific infections are:

    Eye:

    • Blindness
    • Floaters in the eye
    • Visual impairment

    Lung:

    • Pneumonia with impaired oxygen uptake (hypoxia)

    Gastrointestinal:

    • Diarrhea
    • Swallowing difficulties or pain
    • Ulcerations with bleeding

    Brain:

    • Coma
    • Encephalitis with behavioral changes
    • Seizures

    Signs and tests

    Blood and urine tests can detect and measure substances specific to CMV. A tissue biopsy is often required to be certain of the diagnosis (except in the eye or nervous system).