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Coccidioidomycosis - disseminated

  • Alternative Names

    Coccidioidomycosis - systemic


    Most acute infections cause no symptoms. Other times, the symptoms range from mild to severe.

    Symptoms include:

    • Cough
    • Fever
    • Chills
    • Headache
    • Muscle stiffness
    • Muscle aches
    • Neck or shoulder stiffness
    • Change in mental status
    • Sensitivity to light

    Other symptoms that may occur with this disease:

    • Joint swelling
    • Joint pain
    • Skin reaction (erythema nodosum)
    • Arthritis
    • Ankle, feet, and leg swelling

    Signs and tests

    Tests that may be done include:

    • CBC with differential
    • Chest x-ray
    • Coccidioidin skin test
    • Sputum KOH test
    • Coccidioides complement fixation titer to measure antibodies to the Coccidioides fungus in the blood
    • Sputum culture

    A biopsy of tissue may be done to determine the area of disseminated disease:

    • Bone marrow biopsy
    • Liver biopsy
    • Open lung biopsy
    • Skin lesion biopsy

    A brain and nervous system (neurological) examination may show abnormalities.