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Congenital protein C or S deficiency

  • Definition

    Congenital protein C or S deficiency is a lack of proteins C or S in the fluid part of the blood. The proteins are natural substances that help prevent blood clots.


    Alternative Names

    Protein S deficiency; Protein C deficiency


    Causes, incidence, and risk factors

    Congenital protein C or S deficiency is an inherited disorder, which means it is passed down through families. Congenital means it is present at birth.

    The disorder causes abnormal blood clotting.

    About 1 out of every 300 people has one normal gene and one faulty gene for protein C deficiency.

    Protein S deficiency occurs in about 1 in 20,000 people.