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Deep venous thrombosis

  • Alternative Names

    DVT; Blood clot in the legs; Thromboembolism; Post-phlebitic syndrome; Post-thrombotic syndrome

    • Changes in skin color (redness) in one leg
    • Increased warmth in one leg
    • Leg pain in one leg
    • Leg tenderness in one leg
    • Skin that feels warm to the touch
    • Swelling (edema) of one leg

    Signs and tests

    Your health care provider will perform a physical exam. The exam may show a red, swollen, or tender leg.

    The following tests may be done:

    • D-dimer blood test
    • Doppler ultrasound exam of the legs
    • Plethysmography (measurement of blood flow) of the legs
    • X-rays to show veins in the affected area(venography)

    Blood tests may be done to check if there is increased chance of blood clotting (hypercoagulability). Such tests include:

    • Activated protein C resistance (checks for the Factor V Leiden mutation)
    • Antithrombin III levels
    • Antiphospholipid antibodies
    • Genetic testing to look for mutations that make you more likely to develop blood clots, such as the prothrombin G20210A mutation
    • Lupus anticoagulant or
    • Protein C and protein S levels
    • Screening for disseminated intravascular coagulation (DIC)

    This list is not all-inclusive.