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Drug-induced hypothyroidism

  • Symptoms

    Early symptoms:

    • Weakness
    • Fatigue
    • Cold intolerance
    • Constipation
    • Weight gain
    • Depression
    • Brittle fingernails
    • Coarsening and thinning of hair
    • Dry skin
    • Puffy eyes
    Late symptoms:
    • Slow speech
    • Thickening of the skin
    • Puffy face, hands, and feet
    • Decreased hearing ability
    • Thinning of eyebrows
    • Hoarseness
    • Menstrual disorders
    Additional symptoms that may be associated with this disease include joint stiffness.
    Signs and tests

    A physical examination may reveal an enlarged thyroid gland. Your vital signs (temperature, pulse, rate of breathing, blood pressure) may reveal slow heart rate, low blood pressure, and low temperature. A chest x-ray may show an enlarged heart.

    Blood tests to determine thyroid function include:

    • Free T4 test
    • T3 levels
    • TSH (thyroid stimulating hormone)
    Other abnormalities that may be discovered in the laboratory include the following:
    • Increased cholesterol
    • Increased liver enzymes
    • Increased serum prolactin
    • Low serum sodium
    • Low blood glucose
    • CBC that shows anemia