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Ectopic Cushing syndrome

  • Alternative Names

    Cushing syndrome - ectopic


    Symptoms

    Ectopic Cushing syndrome tends to have fewer dramatic symptoms than classic Cushing syndrome, but it can occur with higher blood pressure and a lower potassium level. Weight loss may occur due to cancer.

    Symptoms of Cushing syndrome are:

    • Abdomen sticks out; arms and legs are thin (central obesity)
    • Acne or minor skin infections
    • Buffalo hump
    • Headache
    • Impotence (in men)
    • Increased urination
    • Menstrual cycle stops (in women)
    • Mental changes
    • Purple stretch marks on the skin of the abdomen, thighs, and breasts
    • Round, red, and full face (moon face)
    • Tanning or darkening of the skin
    • Thirst
    • Weakness

    Signs and tests

    Tests that may be done include:

    • 24-hour urine for cortisol and creatinine
    • Blood tests to check ACTH, cortisol, and potassium levels
    • Dexamethasone suppression test
    • Fasting glucose
    • MRI and CT scans to find tumors