Factor V deficiency is an inherited condition that affects the ability of the blood to clot.
Parahemophilia; Owren's disease
Causes, incidence, and risk factors
Normal blood coagulation is a complex process involving as many as 20 different
Factor V deficiency is caused by a lack of the plasma protein Factor V. When certain coagulation factors are low or missing, the chain reaction does not take place normally. Factor V deficiency is rare, and can be caused by inheriting a defective Factor V gene or by acquiring an antibody that interferes with normal Factor V function.
You can acquire an inhibitor of Factor V:
- After giving birth
- After being treated with a certain type of fibrin glue
- After surgery
- With autoimmune diseases and certain cancers
Sometimes the cause is unknown.
The disease is similar to
Excessive bleeding with menstrual periods and after delivery often occurs. Men and women are affected equally. About 1 person per 1 million has the disorder.