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Graves disease

  • Alternative Names

    Diffuse thyrotoxic goiter


    Symptoms
    • Anxiety
    • Breast enlargement in men (possible)
    • Difficulty concentrating
    • Double vision
    • Eyeballs that stick out (exophthalmos)
    • Eye irritation and tearing
    • Fatigue
    • Frequent bowel movements
    • Goiter (possible)
    • Heat intolerance
    • Increased appetite
    • Increased sweating
    • Insomnia
    • Menstrual irregularities in women
    • Muscle weakness
    • Nervousness
    • Rapid or irregular heartbeat (palpitations or arrhythmia)
    • Restlessness and difficulty sleeping
    • Shortness of breath with exertion
    • Tremor
    • Weight loss (rarely, weight gain)

    Signs and tests

    Physical examination shows an increased heart rate. Examination of the neck may show that the thyroid gland is enlarged (goiter).

    Other tests include:

    • Blood tests to measure levels of TSH, T3, and free T4
    • Radioactive iodine uptake

    This disease may also affect the following test results:

    • Orbit CT scan or ultrasound
    • Thyroid stimulating immunoglobulin (TSI)
    • Thyroid peroxidase (TPO) antibody
    • Anti-TSH receptor antibody