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Hemolytic anemia

  • Alternative Names

    Anemia - hemolytic

    • Chills
    • Dark urine
    • Enlarged spleen
    • Fatigue
    • Fever
    • Pale skin color (pallor)
    • Rapid heart rate
    • Shortness of breath
    • Yellow skin color (jaundice)

    Signs and tests

    These are tests for red blood cell destruction (hemolysis). Specific tests can identify the types of hemolytic anemia. They are usually performed when hemolysis is suspected or has been determined.

    • Absolute reticulocyte count
    • Free hemoglobin in the serum or urine
    • Hemosiderin in the urine
    • Red blood cell count (RBC), hemoglobin, and hematocrit (HCT)
    • Serum haptoglobin levels
    • Serum indirect bilirubin levels
    • Serum LDH
    • Urine and fecal urobilinogen

    Directly measuring the red cell life span with radioactive tagging techniques shows a shortened life span.

    This disease may also affect the following test results, depending on the specific cause:

    • AST
    • Coombs' test, direct
    • Coombs' test, indirect
    • Donath-Landsteiner test
    • Febrile or cold agglutinins
    • Leukocyte alkaline phosphatase
    • Peripheral blood smear
    • Platelet count
    • Protein electrophoresis - serum
    • RBC indices
    • Serum creatinine
    • Serum ferritin
    • Serum iron
    • Serum potassium level
    • Serum uric acid
    • TIBC
    • White blood count differential