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IgA nephropathy

  • Alternative Names

    Nephropathy - IgA; Berger's disease


    The goal of treatment is to relieve symptoms and prevent or delay chronic renal failure.

    Medicines may be given to control high blood pressure and swelling (edema). Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are used. Controlling blood pressure is the most important measure to delay kidney damage.

    Corticosteroids, other immunosuppressive drugs, and fish oil have also been used to treat this disorder.

    Salt and fluids may be restricted to control swelling. A low to moderateprotein diet may be recommended in some cases.

    Some people will need to take medicines to lower their cholesterol.

    Eventually, many patients must be treated for chronic kidney disease.

    Support Groups

    For additional information and support, see the IgA Nephropathy Support Network website (www.igansupport.org).

    Expectations (prognosis)

    IgA nephropathy progresses slowly. In many cases, it does not progress at all. High blood pressure, large quantities of protein in the urine, and increased BUN or creatinine levels (blood tests that reflect kidney functioning) indicate a higher risk for progression of the disorder.

    About 25% of adults with IgA nephropathy develop end-stage kidney failure within about 25 years.

    • Acute nephritic syndrome or nephrotic syndrome
    • Chronic kidney failure
    • End-stage kidney disease

    Calling your health care provider

    Call your health care provider if you have bloody urine or if your urine output decreases.