Familial juvenile nephrophthisis; Senior-Loken syndrome
There is no cure for this disease. At first, treatment focuses on controlling symptoms, reducing complications, and slowing the progression of the disease. Because of the loss of water and salt, the patient will need to drink plenty of fluids and take salt supplements to avoid dehydration.
As the disease gets worse, kidney failure develops. Treatment may involve medications and diet changes to limit foods containing phosphorus and potassium. Dialysis and a kidney transplant may be needed. For detailed information on treatment, see the articles on
Most persons with MCKD reach end-stage kidney disease between the ages of 30 and 50. Lifelong treatment may control the symptoms of chronic kidney failure. The cysts associated with MCKD may be very small, but large numbers of them can lead to kidney impairment.
- Bone weakening and fractures
- Changes in glucose metabolism
- Changes in
electrolytelevels ( hyperkalemia)
- Congestive heart failure
- End-stage kidney disease
- Gastrointestinal bleeding, ulcers
High blood pressure
Hyponatremia(low blood sodium level)
- Hyperkalemia (too much potassium in the blood)
- Menstrual irregularities
- Permanent skin coloring changes
- Platelet dysfunction with easy bruising
- Skin coloring changes
- Weakening of the bones, fractures, joint disorders
Calling your health care provider
Call for an appointment with your health care provider if you have any symptoms of medullary cystic disease.