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Megaloblastic anemia

  • Definition

    Megaloblastic anemia is a blood disorder in which there is anemia with larger-than-normal red blood cells.

    Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues.


    Alternative Names

    Anemia - megaloblastic


    Causes, incidence, and risk factors

    Megaloblastic anemia is usually caused by a deficiency of folic acid or vitamin B12.

    Other less common causes are:

    • Alcohol abuse
    • Certain inherited disorders
    • Drugs that affect DNA, such as chemotherapy drugs
    • Leukemia
    • Myelodysplastic syndrome
    • Myelofibrosis

    Risk factors relate to the causes.

    See also:

    • Anemia - B12 deficiency
    • Folate-deficiency anemia
    • Pernicious anemia