Membranoproliferative glomerulonephritis is a kidney disorder that involves inflammation and changes in the microscopic structure of kidney cells. It leads to disrupted kidney function.
Membranoproliferative GN I; Membranoproliferative GN II; Mesangiocapillary glomerulonephritis; Membranoproliferative glomerulonephritis; Lobular GN; Glomerulonephritis - membranoproliferative; MPGN type I; MPGN type II
Causes, incidence, and risk factors
Membranoproliferative GN is a form of glomerulonephritis caused by an abnormal
The changes in this membrane lead disrupt the body's ability to filter urine. Protein and fluid leak out of the blood vessels into body tissues, leading to swelling (
There are two forms of membranoproliferative GN:
- Membranoproliferative GN I
- Membranoproliferative GN II
Most cases are type I. Membranoproliferative GN II is much less common than Membranoproliferative GN I. It also tends to get worse faster than membranoproliferative GN I.
The conditions affect both men and women, mostly under age 30.