Encyclopedia Home / M / Membranoproliferative GN

Membranoproliferative GN

  • Alternative Names

    Membranoproliferative GN I; Membranoproliferative GN II; Mesangiocapillary glomerulonephritis; Membranoproliferative glomerulonephritis; Lobular GN; Glomerulonephritis - membranoproliferative; MPGN type I; MPGN type II


    Treatment

    Treatment depends on the symptoms. The goals of treatment are to reduce symptoms, prevent complications, and slow the progression of the disorder.

    A change in diet may be needed. This may include limiting salt, fluids, or protein to help control high blood pressure, swelling, and the build up of waste products in the blood.

    Medicines that may be prescribed include:

    • Blood pressure medications
    • Cytotoxic medications
    • Dipyridamole with or without aspirin
    • Diuretics
    • Steroids

    Dialysis or kidney transplant may eventually be required to manage kidney failure.


    Support Groups


    Expectations (prognosis)

    The disorder often slowly gets worse and eventually results in chronic kidney failure. Fifty percent of cases lead to chronic renal failure within 10 years.


    Complications
    • Acute renal failure
    • Acute nephritic syndrome
    • Nephrotic syndrome
    • Chronic renal failure

    Calling your health care provider

    Call for an appointment with your health care provider if you have symptoms of this condition. Also call for an appointment with your health care provider if symptoms worsen or persist, or if new symptoms develop, including decreased urine output.