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Membranoproliferative GN II

  • Alternative Names

    Membranoproliferative glomerulonephritis (type II); Glomerulonephritis - membranoproliferative (type II); Mesangiocapillary glomerulonephritis (type II); Dense deposit disease; MPGN II


    Treatment varies according to the symptoms. The goals of treatment are to reduce symptoms, prevent complications, and slow the worsening of the disorder.

    Dietary adjustments may include restrictions on sodium, fluids, protein, or other restrictions to control high blood pressure, swelling, and accumulation of waste products in the bloodstream.

    Antihypertensive medications may be vital to help control blood pressure. Diuretics or other medications may be needed to control swelling or other symptoms.

    Dialysis or kidney transplantation may eventually be required to manage renal failure.

    Support Groups

    Expectations (prognosis)

    The disorder progresses slowly to chronic renal failure. Fifty percent of cases will develop chronic renal failure within 10 years.

    • Acute renal failure
    • Acute nephritic syndrome
    • Nephrotic syndrome
    • Chronic renal failure 

    Calling your health care provider

    Call for an appointment with your health care provider if symptoms indicate MPGN II.

    Call for an appointment with your health care provider if symptoms worsen or new symptoms develop, including decreased urine output.