Myelofibrosis

  • Alternative Names

    Idiopathic myelofibrosis; Myeloid metaplasia; Agnogenic myeloid metaplasia; Primary myelofibrosis; Secondary myelofibrosis


    Symptoms
    • Abdominal fullness related to an enlarged spleen
    • Bone pain
    • Bruising
    • Easy bleeding
    • Fatigue
    • Increased likelihood of getting an infection
    • Pallor
    • Shortness of breath with exercise

    Signs and tests

    Physical examination shows swelling of the spleen. Later in the disease, it may also show an enlarged liver.

    Tests that may be done include:

    • CBC (complete blood count)

    An examination of the blood shows teardrop-shaped red blood cells. Bone marrow biopsy may be done to rule out other causes of the symptoms.