The goals of treatment are to relieve symptoms, prevent complications and delay progressive
Controlling blood pressure is the most important measure to delay kidney damage. The goal is to keep blood pressure at or below 130/80 mmHg. Angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) are the medicines most often used in this case. ACE inhibitors may also help decrease the amount of protein loss in the urine.
Corticosteroids and other drugs that suppress or quiet the immune system may be used.
High cholesterol and levels should be treated to reduce the risk of heart and blood vessel problems. However, a low-fat, low-cholesterol diet is usually not as helpful for people with nephrotic syndrome. Medications to reduce cholesterol and triglycerides may be needed, most commonly statins.
A low salt diet may help with swelling in the hands and legs. Water pills (diuretics) may also help with this problem.
Low protein diets may or may not be helpful. A moderate-protein diet (1 gram of protein per kilogram of body weight per day) may be suggested.
Blood thinners may be required to treat or prevent clot formation.
The outcome varies; the syndrome may be
Atherosclerosisand related heart diseases Renal vein thrombosis Acute kidney failure Chronic kidney disease
- Infections, including pneumococcal
- Fluid overload,
congestive heart failure, pulmonary edema
Calling your health care provider
Call your health care provider if symptoms which may indicate nephrotic syndrome occur.
Call your health care provider if nephrotic syndrome persists or if new symptoms develop, including severe
Go to the emergency room or call the local emergency number (such as 911) if