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Olivopontocerebellar atrophy

  • Definition

    Olivopontocerebellar atrophy is a disease that causes areas deep in the brain, just above the spinal cord, to shrink.


    Alternative Names

    OPCA; Olivopontocerebellar degeneration; Multiple system atrophy – cerebellar predominance; MSA-C


    Causes, incidence, and risk factors

    Olivopontocerebellar atrophy can be passed down through families (inherited form), or it may affect people without a known family history (sporadic form).

    Researchers have identified certain genes that are involved in the inherited form of this condition.

    The cause of olivopontocerebellar atrophy in those without a history of the disease is not known. The disease slowly gets worse (is progressive).

    This disease is slightly more common in men than in women. The average age of onset is 54 years old.