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Pemphigus vulgaris

  • Symptoms

    About 50% of people with this condition first develop painful blisters and sores in the mouth, followed by skin blisters. Skin sores may come and go.

    The skin sores may be described as:

    • Draining
    • Oozing
    • Crusting
    • Peeling or easily detached

    They may be located:

    • In the mouth
    • On the scalp, trunk, or other skin areas

    Signs and tests

    The skin separates easily when the surface of unaffected skin is rubbed sideways with a cotton swab or finger. This is called a positive Nikolsky's sign.

    A skin biopsy is usually done to confirm the diagnosis.