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Plummer-Vinson syndrome

  • Definition

    Plummer-Vinson syndrome is a condition that sometimes occur in people with long-term (chronic) iron deficiency anemia. People with this condition have difficulty swallowing due to small, thin growths of tissue that partially block the upper food pipe, or esophagus.

    Alternative Names

    Paterson-Kelly syndrome; Sideropenic dysphagia; Esophageal web

    Causes, incidence, and risk factors

    The cause of Plummer-Vinson syndrome is unknown. Genetic factors and a lack of certain nutrients (nutritional deficiencies) may play a role. It is a rare disorder that can be linked to cancers of the esophagus and throat. It is more common in women.