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Primary thrombocythemia

  • Alternative Names

    Essential thrombocythemia; Essential thrombocytosis


    Symptoms
    • Bleeding from the gastrointestinal tract, respiratory system, urinary tract, or skin
    • Bleeding from the gums
    • Bleeding (prolonged) from surgical procedures or tooth removal
    • Bloody stools
    • Dizziness
    • Easy bruising
    • Headache
    • Nosebleeds (epistaxis)
    • Numbness of the hands or feet
    • Ulcers on the fingers or toes

    The condition may even cause strokes in some people.


    Signs and tests

    This condition is often detected on blood tests done for other reasons, before there are any symptoms.

    A physical exam may show an enlarged spleen or liver. There may be abnormal blood flow in the toes or feet, as well as skin damage caused by that abnormal blood flow.

    Other tests may include:

    • Bone marrow aspiration and biopsy
    • CBC
    • Genetic tests (to look for a change in the JAK2 gene)
    • Uric acid level