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Proximal renal tubular acidosis

  • Alternative Names

    Renal tubular acidosis - proximal; Type II RTA; RTA - proximal; Renal tubular acidosis type II


    The goal is to restore the normal pH (acid-base level) and electrolyte balance to the body. This will indirectly correct bone disorders and reduce the risk of osteomalacia and osteopenia in adults.

    Some adults may need no treatment. All children need alkaline medication to prevent acid-induced bone disease, such as rickets, and to allow normal growth. The underlying cause should be corrected if it can be found.

    Alkaline medications include sodium bicarbonate and potassium citrate. They correct the acidic condition of the body and correct low blood potassium levels. Thiazide diuretics may indirectly decrease bicarbonate loss but may worsen the low blood potassium levels.

    Vitamin D and calcium supplements may be needed to help reduce skeletal deformities resulting from osteomalacia or rickets.

    Support Groups

    Expectations (prognosis)

    Although the underlying cause of proximal renal tubular acidosis may go away by itself, the effects and complications can be permanent or life-threatening. Treatment is usually successful.


    • Electrolyte imbalances, such as hypokalemia
    • Osteomalacia
    • Rickets

    Calling your health care provider

    Call your health care provider if you have symptoms of proximal renal tubular acidosis.

    Get medical help immediately if you develop any of the following emergency symptoms:

    • Decreased alertness or orientation
    • Decreased consciousness
    • Seizures