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Renal papillary necrosis

  • Definition

    Renal papillary necrosis is a disorder of the kidneys in which all or part renal papillae die. The renal papillae is the area where the openings of the collecting ducts enter the kidney.


    Alternative Names

    Necrosis - renal papillae; Renal medullary necrosis


    Causes, incidence, and risk factors

    Renal papillary necrosis is most commonly associated with analgesic nephropathy. However, a number of conditions can cause this condition, including:

    • Diabetic nephropathy
    • Kidney infection
    • Kidney transplant rejection
    • Urinary tract obstruction
    • Sickle cell anemia

    Sickle cell anemia is a common cause of renal papillary necrosis in children.