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Sjogren syndrome

  • Definition

    Sjogren syndrome is an autoimmune disorder in which the glands that produce tears and saliva are destroyed. The condition may affect many different parts of the body, including the kidneys and lungs.

    Alternative Names

    Xerostomia-Sjogren syndrome; Keratoconjunctivitis sicca - Sjogren's

    Causes, incidence, and risk factors

    The cause of Sjogren syndrome is unknown. The syndrome occurs most often in women ages 40 - 50. It is rare in children. Young patients usually have signs of another autoimmune disorder first.

    The syndrome may be associated with:

    • Polymyositis
    • Rheumatoid arthritis
    • Scleroderma
    • Systemic lupus erythematosus

    Sjogren syndrome affects about 1 - 4 million people in the United States.