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Sjogren syndrome

  • Alternative Names

    Xerostomia-Sjogren syndrome; Keratoconjunctivitis sicca - Sjogren's


    Dryness of the mouth and eyes are the most common symptoms of this syndrome.

    Eye symptoms:

    • Itching eyes
    • Feeling that something is in the eye

    Mouth and throat symptoms:

    • Difficulty swallowing or eating
    • Loss of sense of taste
    • Difficulty speaking
    • Thick or stringy saliva
    • Mouth sores or pain
    • Hoarseness

    Other symptoms may include:

    • Fatigue
    • Fever
    • Change in the color of hands or feet
    • Joint pain or joint swelling
    • Swollen glands

    Signs and tests

    A physical examination reveals dry eyes and mouth. There may be mouth sores because of the mouth dryness.


    • Schirmer's test
    • Antinuclear antibodies (ANA) test
    • Salivary gland biopsy
    • Rheumatoid factor (possible)
    • Tear test
    • Slit lamp examination with rose bengal dye