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Testicular failure

  • Definition

    Testicular failure is the inability of the testicles to produce sperm or male hormones.

    See also:

    • Hypogonadism
    • Secondary hypogonadism

    Alternative Names

    Primary hypogonadism - male


    Causes, incidence, and risk factors

    Testicular failure is uncommon. Causes include:

    • Certain drugs, including glucocorticoids, ketoconazole, and opioids
    • Chromosome problems
    • Diseases that affect the testicle, including mumps, orchitis, and testicular cancer
    • Injury to the testicles
    • Testicular torsion

    The following things increase the risk for testicular failure:

    • Activities that may cause constant, low-level injury to the scrotum, such as riding a motorcycle
    • Frequent and heavy use of marijuana
    • Undescended testicles at birth