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Thrombotic thrombocytopenic purpura

  • Alternative Names

    TTP ADAMTS13


    Symptoms
    • Bleeding into the skin or mucus membranes
    • Changes in consciousness
    • Confusion
    • Easy fatigue
    • Fever
    • Headache
    • Heart rate over 100 beats per minute
    • Pallor
    • Purplish spots in the skin produced by small bleeding vessels near the surface of the skin (purpura)
    • Shortness of breath
    • Speech changes
    • Weakness
    • Yellowish color to the skin (jaundice)

    Signs and tests
    • ADAMTS 13 activity level
    • Bilirubin
    • Blood smear
    • CBC
    • Creatinine level
    • Lactate dehydrogenase (LDH) level
    • Mucus membrane biopsy
    • Platelet count
    • Urinalysis
    • Von Willebrand factor electropheresis