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Toxic nodular goiter

  • Definition

    Toxic nodular goiter involves an enlarged thyroid gland that contains a small rounded growth or growths called nodules. These nodules produce too much thyroid hormone.


    Alternative Names

    Toxic multinodular goiter; Plummer's disease


    Causes, incidence, and risk factors

    Toxic nodular goiter arises from an existing simple goiter. It occurs most often in the elderly. Risk factors include being female and over 60 years old. This disorder is never seen in children.

    Sometimes patients with toxic multinodular goiter will develop high thyroid levels for the first time after they receive a large amount of iodine through a vein (intravenously). The iodine may be contrast for a CT scan or heart catheterization.