Frequent sinusitis is the most common symptom. Other early symptoms include a fever that continues without an obvious cause, night sweats,
Chronic ear infections are common. Other upper respiratory symptoms include nose bleeds, pain, and sores around the opening of the nose.
Loss of appetite and weight loss are common. Skin changes are also common, but there is no one typical lesion associated with the disease.
There may be symptoms of kidney disease. The urine may be bloody.
Eye problems develop in many people with Wegener's granulomatosis. The eye problems range from mild
Other symptoms include:
- Chest pain
- Cough, with or without blood
- Joint pain
- Shortness of breath
Signs and tests
Your doctor may order a blood test that looks for proteins called antineutrophil cytoplasmic antibodies (ANCA), which are often found in people with active Wegener's granulomatosis. However, it is not foolproof -- the test may be negative in some patients.
- Bronchoscopy with biopsy
- Kidney biopsy
Nasal mucosal biopsy Open lung biopsy
- Skin biopsy
Upper airway biopsy
Other tests that may be done include:
Bone marrow aspiration
- Chest CT scan