You've seen the commercials for Cialis (tadalafil) and the joy it promises to bring to some men struggling from erectile dysfunction. Well, when you add tadalafil to other standard treatments for Reynaud's disease, it seems to help and is well tolerated. If you're not familiar with Reynaud's, it's a condition where the person's blood vessels narrow suddenly and abnormally, particularly when exposed to cold. People who suffer with this condition typically get tingling in their fingers and fingertips, and you can actually see a color change to white and blue. You can develop ulcers that heal poorly because of the circulation compromise. You can have this disease alone (primary) or associated with other autoimmune conditions (secondary) like scleroderma and lupus. About 5% of the population suffers from primary Reynaud's.
The study involved 25 patients and 24 patients completed the full study. The results were compelling. In those who had tadalafil 20 mg every other day added to their treatment regimen, the average daily frequency and duration of Reynaud's episodes decreased. Severity of the disease decreased as well. Additionally, none of the patients who took Cialis had any significant side effects. And patients with the ulcers seemed to benefit as well. The study recommends that patients with this condition talk to their rheumatologists about this treatment possibility.
Published On: October 27, 2008