Researchers at Duke University Medical Center have now figured out how the HSV1 - the cause of cold sores - manages to hide out. Apparently they lie dormant in the trigeminal nerve of the face until they are triggered by excessive sunlight, a fever or other stresses.
Well now that scientists are beginning to understand how the virus switches back and forth from dormant to active phase, and this could lead to a cure. When the virus gets stimulated it creates new molecular material (RNA) and replicates and then goes out on its so-called "new mission" - hence the cold sores. If scientists can create a drug that binds to the RNA and stimulates the replication, you essentially activate the virus and then kill the virus by having the patient take acyclovir. You would then have a situation where a virus was eradicated for good.
This would be huge since HSV1 is certainly a communicable disease and can be transferred by kissing, oral sex, sharing utensils or towels. Drug trials to begin developing microRna stimulators are now in the works. Stay tuned for more!!
Published On: July 07, 2008