Saturday, May 26, 2012
Thursday, August 21, 2008 confused1 asks

Q: still confused....

Whoever answered my question "tested negative for years...now tests positive", thank you. Unfortunately, although it gave valuable information, it did not answer my question.

My question is...if antibodies take 12-16 weeks to develop after exposure, and blood tests test for antibodies, then how is it possible to test negative multiple times over the years, then test positive about an exposure twenty years ago. I don't understand why the antibodies didn't show up until now (the last two people I've been in relationships with recently tested negative) Is it possible to be exposed and contagious for years with no symptoms AND negative blood work. That is what my gynocologist says is possible

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Answers (2)
8/23/08 6:30pm

i'm going to attempt an answer for you...

when a virus enters the human cell it injects it's DNA into your cell and it's DNA attachs to your DNA strand. Your cell divides through mitosis which means they duplicate themselves constantly. They also duplicate the DNA of the virus attached to your DNA. This duplication can happen for years while the virus is dorment, but the virus is not active until the DNA virus separates from your DNA and uses the cell parts to make new virus. (It's like they clone themselves inside the cell). When the virus is dorment however, the virus DNA in present in the dead skin cells in the area it entered your body and the virus is techniqely not alive, but it's DNA can transfer to a living cell on another person's body. This is my understanding of the situation as I got it from my boyfriend who has no symptons. Ask your doctor about this explination and if this doesn't make any sense, then tell your doctor to explain it in a different way.

 

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8/24/08 6:12am

part 2

 

basically when the virus is dormant, your body doesn't have to produce antibodies to combat it. It only produces antibodies when the virus is active. Blood tests are done to see if there are any antibodies for herpes present. If the virus is active, then there would be, but if the virus is not active (dormant) then there is little chance that there would be any antibodies present. 

This explination helped me understand it, maybe it will help you too.

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By confused1— Last Modified: 12/19/10, First Published: 08/21/08