Researchers say a molecule known as surfen has shown potential to be an active ingredient in a topical treatment designed to prevent the spread of HIV from semen. Though HIV is difficult to treat once it's entered the body, it struggles to infect during sexual transmission. Because of this, researchers say the small molecule surfen could make HIV infection more unlikely by interfering with the action of a factor in semen called "semen-derived enhancer of viral infection," or SEVI.
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