Saturday, May 18, 2013

Coumadin: Generic Versus Brand Name

By Deanne Stein, Health Guide Wednesday, November 21, 2007
It's been seven weeks since I had my baby. The time is really flying by and soon my maternity leave will be over. I've been slowly getting back to normal since pregnancy. My hormones are calming down, the nausea is gone and it's nice not to be waddling anymore. The baby w...
12/ 9/07 3:53pm

Dear Deanne,

 

The problem is that even though all companies are held to strict tolerances as to variance of dosage amount in their warfarin tablets, they are not held to not varying from company to company.

 

Though you can be confident that there is very little variability from one tablet to another from the same company, going from one company to another as happens with generics introduces unregulated variability.

 

Put a different way, there is little intracompany variability but unpredictable intercompany variability in warfarin dose for their respective warfarin tablets (5 mg in your specific case).

 

Solution:

 

Here is what we do in our cardiac clinic...

 

... we switch folks from ordinary generics to a branded generic.

 

The latter is from a company that has recognized the above problem and has opted to use this their competitive edge.  They make warfarin and retail it at the same price as the generic companies but have a brand name that a doctor can prescribe as brand necessary.

 

The branded generic we prescribe is Jantoven made by Upsher-Smith:

 

http://www.jantoven.com/about.html

 

Disclosure: No financial ties with Upsher-Smith.

 

Hope this information proves helpful in saving some money for you and your insurance company. 

 

Congratulations on the new addition to your family :-)

1/18/12 5:44pm

I had a terrible reaction to warfarin after taking it for several months when the druggist had a different supplier  and  my doctor without a doubt said it was because the inactive ingredients can be different in the generic.  He ordered strictly coumadin for me, no exceptions, and I have had no problems since.  I would never go back to warfarin.

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By Deanne Stein, Health Guide— Last Modified: 08/09/12, First Published: 11/21/07